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The peptide blocks ferritin channels, preventing release of tissue-damaging free iron after tissue injury

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The importance of this pathway is not only crucial for ferroptosis as cystathionase is also described to be involved in senescence evasion in melanocytes and melanoma cells (56)

Confocal microscopy images were obtained as described previously 49

BPC-157 appears to preserve this pathway even when animals are pre-treated with nitric oxide synthase inhibitors, suggesting it acts at multiple points in the cascade rather than through a single enzyme

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